Jamestown Regional Medical Center

Jamestown Regional Medical Center Logo Located in Tennessee’s Fentress County, Jamestown is only 70 miles from Chattanooga and 45 miles from Cookeville. The area is abundant in natural beauty and has a small-town atmosphere where residents enjoy good home cooking at local restaurants and unique shopping opportunities. Located 75 miles from Knoxville, less than 30 miles from Monticello, Kentucky, and less than 115 miles from Lexington, Kentucky, Jamestown is nestled in the beautiful Upper Cumberland Region of Tennessee. Jamestown's home county is also home to the Big South Fork National River and Recreation Area, Sgt. Alvin C. York State Historical Site, and Pickett State Park. Fentress County is known as the Trail Riding Capitol of the Southeast!